The Brain Matters Research Facility in Delray Beach, Florida is one of the nation’s largest private research organizations and stands at the forefront of Alzheimer’s disease research.  Brain Matters Research conducts a vital segment of medical research that seeks  to identify new treatments and markers for the 5th leading cause of death in America today.   The Brain Matters Research team has established a lengthy track record of major contributions and is the leader in Alzheimer’s disease research conducting over 300 clinical trials over the past 20 years.

Brain Matters Research has become nationally recognized for its identification of novel leading  edge therapies for  Alzheimer’s disease and other memory disorders, such as Mild Cognitive Impairment and Age Associated Memory Impairment.  Other areas of study include primary and secondary prevention of stroke, Parkinson’s disease research, Neuropathy research and Familial history and prevention of Alzheimer’s disease.

Prevention Articles:

Dementia Studies Find Diet, Exercise Matter - Two studies published in this week's Journal of the American Medical Association add to evidence that long-term lifestyle habits may reduce the risk of mental decline in old age... Read More...


Pharmacokinetics and Pharmacodynamics of Bapineuzumab Following Multiple Intravneous Infusions in Patients with Mild to Moderate Alzheimer’s Disease - Background: Bapineuzumab, a humanized anti-amyloid-beta (AB) peptide monoclonal antibody, is under investigation for the treatment of Alzheimer's Disease (AD). Bapineuzumab is hypothesized to reduce AB from the brain and lead to a beneficial clinical effect.  Read More...


Plasma Phosphatidylcholine Docosahexaenoic Acid Content and Risk of Dementia and Alzheimer Disease- Background:  Docosahexaenoic acid (DHA) is an abundant fatty acid in the brain. In the diet, DHA is found mostly in fatty fish. The content of DHA has been shown to be decreased in the brain and plasma of patients with dementia.  Read More...


Training the Elderly on the Ability Factors of Spatial Orientation and Inductive Reasoning - We examined the effects of cognitive training with elderly participants from the Seattle Longitudinal Study.  Read More...


Stronger, Faster, Smarter - The stereotype of the "dumb jock" has never sounded right to Charles Hillman. A jock himself, he plays hockey four times a week, but when he isn't body-checking his opponents on the ice, he's giving his mind a comparable workout in his neuroscience and kinesiology lab at the University of Illinois.  Read More...


Training early Alzheimer Patients to Use a Mobile Phone - The mobile phone may be useful to keep in contact with spatially disoriented and memory impaired patients.  Read More...


Rote Learning Improves Memory in Seniors - Researchers have found a simple way for older adults to combat memory loss-memorization.  Seniors who engaged in an intensive period of rote learning followed by an equally long rest period exhibited improved memory and verbal recall. Read More...


Exercise and the Brain: Angiogenesis in the Adult Rat Cerebellum After Vigerous Physical Activity and Motor Skill Learning - This study compared the morphology of cerebellar cortex in adult female rats exposed for 1 month to repetitive exercise, motor learning, or an inactive condition.  Read More...


Diabetes Mellitus and Risk of Developing Alzheimer Disease - Background:  Diabetes mellitus (DM) could increase the risk of Alzheimer disease (AD) through several biologically plausible pathways, but the relationship between DM and the development of AD remains uncertain.  Read More...


A strategy to reduce cardiovascular disease by more than 80% - Objectives: To determine the combination of drugs and vitamins, and their doses, for use in a single daily pill to achieve a large effect in preventing cardiovascular disease with minimal adverse effects.  Read More...


A Cognitive Intervention Trial to Promote Independence in Older Adults - The Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) trial is a randomized, controlled, single-masked trial designed to determine whether cognitive training interventions (memory, reasoning, and speed of information processing), which have previously been found to be successful at improving mental abilities under laboratory or small-scale field conditions, can affect cognitively based measures of daily functioning.  Read More...